Is Ativan Safe During Pregnancy?

2 min read · 6 sections

Treating anxiety during pregnancy can be challenging, especially if the mother has been using psychiatric drugs that could threaten her health or the health of her baby. Ativan (lorazepam) belongs to a class of tranquilizing medications called benzodiazepines, which are among the most commonly prescribed psychiatric drugs in the US. If you are a pregnant person and are wondering “is Ativan safe during pregnancy?” this page will explain some of the risks and benefits, safe treatments for anxiety, and how to get help if you or a loved one is struggling with Ativan addiction.

What Is Ativan?

Ativan is a central nervous system depressant that is prescribed to treat several serious conditions, including anxiety, insomnia, seizure disorders, muscle spasms, and alcohol withdrawal syndrome.

Ativan is also administered in hospitals or surgical centers to help patients relax before surgery. Like other drugs in the benzodiazepine family–diazepam (Valium), alprazolam (Xanax), and clonazepam (Klonopin), to name a few–Ativan has the potential to be addictive. Although Ativan is safe for most adults, use of this medication should be approached with caution in pregnant women, especially those who have a history of substance misuse or addiction.

Pregnancy and Anxiety

Weighing the risks and benefits of Ativan use in pregnancy should be a collaborative effort between the patient and her physician. While lorazepam does present the possibility of certain complications and birth defects, leaving anxiety untreated can also have negative repercussions for a pregnant woman and her baby.

American Family Physician estimates that approximately half a million pregnant American women suffer from psychiatric disorders during their pregnancy. Many anxiety disorders, including generalized anxiety disorder, panic disorder, social anxiety disorder, and agoraphobia, are more common in women than in men. Pregnancy can trigger anxiety symptoms or make anxiety worse, especially in women who don’t have a strong social support network or who are faced with financial or social stress.

Risks vs. Benefits of Ativan

Research has not established a strong relationship between Ativan use and serious complications of pregnancy, such as premature labor or damage to the placenta. There are a limited number of studies have shown that Ativan may increase the risk of preterm labor and low birth weight. Additionally:

  • Most of the health risks of Ativan affect developing infants and newborn babies. Lorazepam has been associated with a slightly higher than average (0.7 percent) risk of cleft lip and cleft palate in newborns, according to the National Institute on Drug Abuse.
  • There is a risk of drug withdrawal in infants whose mothers have been using Ativan. Withdrawal symptoms can include: sedation, difficulty breathing, irritability, and “floppy baby syndrome.”
  • Because small amounts of Ativan are passed from mother to baby in breast milk, the medication is also not advised for breastfeeding women due to a risk of over-sedation in the infant.

In a few cases, seizures have been reported in infants who were withdrawing from the effects of benzodiazepines, but these incidents are rare. Serious signs of Ativan toxicity are more common in babies whose mothers are heavy users of this drug. Women who take Ativan with alcohol, opiates, or street drugs during pregnancy increase the risk of complications with pregnancy, premature delivery, low birth weight, and birth defects even further.

Effects of Untreated Anxiety on Pregnancy

There is an association between low birth weight, complications, and maternal anxiety, making it important to identify and find safe interventions. According to recent studies, untreated anxiety in pregnant people can result in a number of effects on the infant, including:

  • Low birth weight and height.
  • Prolonged crying, irritability, and restlessness.
  • Rash, shortness of breath, and asthma.

Pregnant people struggling with mental illness may be less likely to follow nutritional guidelines, take prenatal vitamins, or attend their prenatal checkups. American Family Physician adds that complications with pregnancy, such as premature delivery and miscarriage, are also more common among pregnant people with anxiety disorders. Finding an alternative to Ativan and other potentially harmful drugs may be the most effective way to ensure a healthy pregnancy.

Safe Treatments for Anxiety

Anxiety can be a serious problem during pregnancy, especially if the disorder is not treated, but not all treatments and medications are safe for pregnant people or their developing babies. Unfortunately, many pregnant women do not report their symptoms to a healthcare provider or loved one, and many do not receive treatment. However, there are safe treatments for anxiety.

Safe and effective therapeutic modalities for people during pregnancy include:

  • Less habit-forming medications with a lower risk of birth defects, such as antidepressants in the SSRI (selective serotonin reuptake inhibitor) category.
  • Cognitive Behavioral Therapy (CBT), a learning-based approach that helps clients unlearn negative thought patterns and replace them with more positive, self-affirming thoughts and actions.
  • Holistic therapies such as prenatal massage, meditation, or prenatal yoga, which provide techniques for self-relaxation.
  • Nutritional counseling to prevent nutrient deficiencies that might contribute to emotional stress or jeopardize the health of the mother and baby.
  • Psychosocial services to link pregnant women with financial and legal support, access to housing and transportation, and affordable childcare.

Ativan Misuse During Pregnancy

Prescription drug abuse is a growing problem in the US, and pregnant women have also been affected by this trend. According to the 2020 National Survey on Drug Use and Health, past month misuse of prescription tranquilizers or sedatives among pregnant people was .20%.  Although Ativan misuse poses serious health risks during pregnancy, stopping the drug too quickly could lead to dangerous withdrawal symptoms.

Ativan Addiction Treatment

Pregnancy shouldn’t be a stressful time of life, but for many women, the experiences surrounding pregnancy and childbirth can be emotionally trying which is why women need the support of compassionate and knowledgable professionals.

If you are pregnant, or wish to become pregnant, and are struggling with Ativan misuse or addiction, it’s important to reach out to your healthcare professional to work together to develop a treatment plan that can keep you and baby safe and healthy. Recovery is possible, so don’t wait.

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