Anabolic Steroid & Corticosteroid Withdrawal: Signs, Symptoms & Treatment

2 min read · 3 sections

There are two kinds of steroids that are targets for misuse: anabolic steroids and corticosteroids.

Anabolic steroids help to build muscle and are considered performance-enhancing drugs. Corticosteroids, which block allergic reactions and inflammation related to allergic reactions, are related to cortisol, which is produced by the adrenal glands. Typically, anabolic steroids are misused more frequently, but corticosteroids have been associated with substance use as well.

Anabolic Steroid Misuse and Withdrawal

Anabolic steroids are similar to testosterone, a male hormone that enhances muscle tone and growth. As medicines, these drugs are taken orally in pill form, shot into a muscle with a needle, or absorbed through the skin via a gel or cream.

People who struggle with anabolic steroid use typically want to develop larger muscles, increase strength, and lower body fat. Unlike other kinds of substance use, anabolic steroid misuse is specifically about enhancing appearance, with no other associated euphoria. Teenage boys are more likely to struggle with anabolic steroid use, often due to body dysmorphia.

Anabolic steroids may also produce hedonic effects, which are pleasurable feelings of power, aggression, and self-confidence. These effects are different than euphoria. They may wear off as the dose of steroid wears off, reinforcing the desire to take more of the substance.

It is important to stop misusing anabolic steroids before life-threatening conditions occur. Working with a doctor to taper the amount of steroid ingested is very important.

Quitting the drug suddenly can lead to relapse and acute physical harm.

Symptoms from withdrawal from anabolic steroids include:

  • Mood swings
  • Serious depression
  • Fatigue and excessive sleeping
  • Restlessness
  • Loss of appetite
  • Trouble sleeping or insomnia
  • Decreased sex drive
  • Cravings for steroids

If a person presents with manic or psychotic symptoms before or early in the detox process, their doctor may prescribe small amounts of antipsychotic or anti-manic medicines to ease their withdrawal symptom. Psychosis related to steroid use typically resolves after two weeks at most, so long-term prescriptions are not necessary.

The most problematic symptom during anabolic steroid withdrawal is depression, so this condition may be treated with an SSRI antidepressant if it persists after the detox process is complete. Long-term physical changes like infertility or sex drive issues may be treated with hormone therapy if they are distressing.

Corticosteroid Misuse and Withdrawal

People who struggle with prescription drug use may take non-medical amounts of prednisone or other corticosteroids. Although these substances are not believed to be addictive, they do affect the amount of cortisol available to the brain, and eventually, the brain will reduce how much cortisol it produces naturally. This can lead to dependence on corticosteroids, which can cause withdrawal symptoms.

Symptoms of corticosteroid withdrawal include:

  • Intense fatigue
  • Physical weakness
  • Muscle aches
  • Joint pain
  • Appetite and weight loss
  • Nausea and vomiting
  • Diarrhea
  • Abdominal pain

Acute withdrawal symptoms typically go away within one week after stopping prednisone and other corticosteroids; however, a doctor will likely taper the medication to prevent serious withdrawal or a protracted withdrawal syndrome.

A taper allows the brain to become re-accustomed to producing a sufficient amount of cortisol without the help of medication.

Treatment for Steroid Misuse

Detoxing from steroids is the first step in getting appropriate treatment; after that, many people have found behavioral therapy, in both individual and group sessions, to be helpful to understanding the impulse to use substances. People who struggle with anabolic steroid misuse may also have underlying body image problems or depression, which contributed to the substance use, and it is important to seek out a rehabilitation program that specializes in co-occurring disorders. Appropriate psychotherapy to help with depression or body dysmorphia should continue after the rehabilitation program is completed.

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