Hydrocodone Withdrawal Symptoms, Timeline & Detox Treatment

3 min read · 5 sections

Hydrocodone is an opioid drug that affects levels of dopamine in the brain. When an individual takes hydrocodone regularly for a length of time, they may develop tolerance to the drug, and in order to continue to feel its desired effects, more will need to be taken. Taking increasingly large amounts of hydrocodone may lead to the swift development of physical dependence, however, and ultimately, addiction.

Hydrocodone is the primary active component of several common prescription painkillers, including the widely available Vicodin. Hydrocodone products are the most commonly prescribed drugs in America, according to Consumer Reports. Because of the high potential for diversion and abuse, not to mention addiction liability, hydrocodone products were moved to the more tightly controlled Schedule II Drug Enforcement Administration (DEA) classification after the Food and Drug Administration (FDA) completed a scientific review and requested the change in 2013.

Prescription medications can be beneficial. They can diminish symptoms such as pain and fever and ultimately help people heal. However, individuals can develop an unhealthy dependence on certain prescriptions, such as hydrocodone, especially when misused. At American Addiction Centers, we provide medical detox, along with treatment and ongoing support. If you’re struggling with an active addiction to opioids or other drugs, please connect with one of our admissions navigators at Don’t wait to get the help you need today!

Hydrocodone Withdrawal Symptoms

Side effects of hydrocodone withdrawal range from mild to moderate to severe and may differ from person to person. Just as the withdrawal timeline can be influenced by the level of dependency the brain exhibits to hydrocodone, so can the intensity and variety of withdrawal symptoms.

Opiate drugs bind to the multiple opioid receptors throughout the brain and central nervous system, and they act to depress certain physiological processes—resulting in a reduction in breathing rate, heart rate, blood pressure, and body temperature. When someone is dependent on an opioid drug like hydrocodone, the sudden removal of it can have distressing consequences as the brain and body work in overdrive to recover. Blood pressure, respiration, body temperature, and heart rate may all spike if hydrocodone use or abuse is stopped suddenly. It is therefore not recommended to stop taking a hydrocodone product “cold turkey” or without medical supervision and input.

Specific withdrawal symptoms when stopping hydrocodone may include:

  • Muscle aches
  • Runny nose
  • Excessive tearing
  • Nausea and abdominal cramps
  • Sweating
  • Chills
  • Goosebumps
  • Trouble sleeping
  • Yawning
  • Vomiting
  • Diarrhea
  • Irregular heart rate
  • Difficulties focusing or concentrating
  • Anxiety
  • Irritability
  • Headache
  • Restlessness
  • Mood swings
  • Trouble feeling pleasure
  • Depression
  • Agitation
  • Night sweats
  • Fatigue
  • High blood pressure
  • Drug cravings
  • Thoughts of suicide

Hydrocodone Withdrawal Timeline

doctor helping patient

Most hydrocodone products, including Norco and Vicodin, are immediate release formulations, with a duration of effects lasting roughly 4-6 hours, the Journal of Pain Research publishes, although there are a few extended-release varieties that last up to 12 hours per dose, which could slightly delay the onset of withdrawal.

Generally speaking, hydrocodone withdrawal will start between 6 and 12 hours after the last dose, depending on which specific drug the dependent individual last took. Opioid withdrawal usually peaks within 72 hours and can last anywhere from a week to a month. Drug cravings and some of the emotional side effects may last longer than a month.

The amount of time an individual took hydrocodone, as well as the average dose and exact formulation of the drug may make a difference in the precise withdrawal timeline and severity. The longer a drug is taken, the more likely that significant physiological dependence has developed. Some underlying medical or mental health issues may also change how long withdrawal will last, as the brain works to restore itself to where it was before hydrocodone was introduced.

hydrocodone withdrawal timeline infographic

Medications for Hydrocodone Dependence Treatment

hydrocodone addiction medication

Abruptly quitting an opioid like hydrocodone may result in the onset of very unpleasant withdrawal symptoms.

If a person develops dependence as a result of chronic prescription use, their doctor may first attempt to slowly taper the doses to minimize the severity of the associated withdrawal syndrome. There are also several medications approved to manage opioid dependence, which include:

Hydrocodone Detox & Treatment for Hydrocodone Withdrawal

In many cases of hydrocodone addiction, medical detox helps keep the individual comfortable as the drug clears from the body. Detox can be performed in either an outpatient or inpatient capacity, with a medical professional monitoring withdrawal progress.

Medical detox is the optimal choice for helping to minimize hydrocodone withdrawal and ensure an individual’s safety and comfort. Hydrocodone detox programs monitor vital signs and use medications to keep patients comfortable and stable for a period of 5-7 days in most cases. There are several pharmaceutical options used during medical detox from hydrocodone that reduce withdrawal symptoms and help to prevent relapse in part by lowering the amount and intensity of drug cravings.

A hydrocodone detox program first works to stabilize an individual physically, and generally lasts about a week. A comprehensive hydrocodone detox center will likely include both pharmaceuticals and holistic methods to accomplish this. For instance, a healthy diet plan, exercise program, and structured sleep schedule may all be included at a medical detox center to help the body heal faster, as may meditation, yoga, spa treatments, and/or massage therapy. Detox is likely to be smoother and go faster if all physical elements are attended to so that the psychological side effects of withdrawal and addiction can be managed as well.

The detox center should be only one part of a more comprehensive substance abuse treatment plan that will also include therapy, counseling, and relapse prevention techniques.

Find a Hydrocodone Detox Center Near You

Need more info?
Get in touch with us via one of these free and confidential options.
Call Us 24/7
Verify Your Insurance
Need more info?
Get in touch with us via one of these free and confidential options.
Take the first step towards recovery.
Make the process simple. Ensure your benefits cover treatment.
Need more info?
Get in touch with us via one of these free and confidential options.
Take control of your life today.
Save time. See if your insurance covers treatment.
Need more info?
Get in touch with us via one of these free and confidential options.
We're here to listen. Speak to our compassionate navigators.
Let's work together to verify your coverage for treatment.