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The Effects of Alcohol On Your Body: Side Effects, Dangers & Health Risks

alcohol and the body

Alcohol is the second most widely used substance in the U.S., behind tobacco. According to the 2019 National Survey on Drug Use and Health, approximately 86% of Americans ages 18 and older reported using alcohol at some point in their lifetime.1

Although alcohol can make a person feel happy, pleasant, and sociable in short periods of time, excessive or chronic, long-term drinking can lead to alcohol dependence or alcohol addiction, officially referred to as an alcohol use disorder. Chronic alcohol use is also associated with other cognitive and mental health issues, including problems with learning or memory as well as exacerbating or causing serious mental health issues like depression and anxiety.2,3

Alcohol doesn’t just affect the mind; it also affects the body. Evidence suggests that even drinking within recommended limits may increase a person’s overall risk of death from various causes, such as from several types of cancer and certain forms of cardiovascular disease.4 This article will help you understand how alcohol affects your physical health as well as answer many common questions about alcohol and its short-term and long-term effects on the body.

Short-Term Effects of Alcohol on the Body

When you ingest even a small amount of alcohol, your body reacts in several ways:7,11,12,13,14,15

  • Brain: Alcohol slows down the chemicals and pathways your brain uses to control your body, altering mood, slowing down reflexes and affecting balance. It also can contribute to learning, memory, and sleep problems.
  • Heart: Alcohol increases your heart rate and expands your blood vessels, making more blood flow to the skin (which causes you to feel warm), however, this heat passes out through the skin, causing body temperature to fall after it has risen.
  • Digestive: Alcohol is first broken down in the stomach, promoting an increase in digestive juices. Alcohol also irritates the small intestine and colon where it is further broken down and absorbed, and it also can affect the normal speed that food moves through them, which may result in abdominal pain, bloating, and diarrhea.
  • Kidney: Alcohol dries out (i.e., dehydrates) the body, which can affect the kidneys and the body’s ability to regulate fluid and electrolytes. It also disrupts hormones that affect kidney function.
  • Liver: Alcohol—most of it, in fact—is metabolized in the liver, which filters circulating blood and removes and destroys toxic substances, including alcohol. The liver can handle a certain amount of alcohol, but as a person continues to drink, it can become stressed to the point of causing permanent damage.

Drinking excessively within a short period of time, or binge drinking, increases the stress on your body and internal organs (and can result in feeling a hangover following a drinking session). High levels of alcohol in your body can result in headaches, severe dehydration, nausea, vomiting, diarrhea, and indigestion.3

Drinking excessively, even on a single occasion, increases a person’s risk of detrimental heart effects. These effects include:16

  • Cardiomyopathy, which means that your heart muscle has a harder time pumping blood.
  • Arrhythmias, which is an irregular heartbeat.
  • High blood pressure.
  • Stroke.

Excessive alcohol use on a single occasion can also put you at risk of alcohol poisoning. This can occur when your body is overwhelmed by the amount of alcohol you drank and is no longer able to effectively process it from your system. You can experience a negative impact on your breath rate, heart rate, and gag reflex. Severe alcohol poisoning can lead to a coma and even death.3

Long-Term Effects of Alcohol on the Body

When you drink excessively and over long periods of time, alcohol can potentially damage many vital organ systems in your body. These health risks include: 3,16,17,18,19

  • Cardiovascular health risks. In addition to the previously mentioned cardiovascular effects and risk of heart damage, excessive alcohol use can raise your cholesterol levels.
  • Brain health risks. The long-term effects of alcohol on the brain can cause an impact on memory, learning, and behavior. Alcohol abuse can result in:
    • Brain shrinkage.
    • Loss of grey matter.
    • Loss of white matter.
  • Liver health risks. Your liver is a strong organ, but it cannot keep up with long-term, excessive alcohol use, which increases the risk of:
    • Fatty liver (steatosis).
    • Alcoholic hepatitis.
    • Fibrosis.
    • Cirrhosis.
    • Liver cancer.
  • Pancreatic health risks, including vitamin deficiencies. Alcohol is associated with vitamin deficiencies due to malabsorption and poor dietary intake. Chronic alcohol consumption may contribute to developing pancreatitis, which means inflammation and blood vessel swelling of the pancreas. This can harm your ability to digest food and absorb nutrients.
  • Immune system risks. Drinking too much for too long can impair your body’s ability to fight infection and disease.
  • Increased likelihood of cancer. The development of many different types of cancers can be influenced by alcohol, a known carcinogen. Clear evidence suggests that heavy alcohol use (particularly in association with smoking) can affect the development of and increase the risk of breast, liver, esophageal, head and neck, and colorectal cancer. Emerging evidence is also pointing to an increased risk of melanoma, prostate, and pancreatic cancer. The National Cancer Institute reports that alcohol can increase the risk of head and neck cancer by at least 2-3 times in people who have 3.5 or more drinks per day.
  • Musculoskeletal health risks. Alcohol can weaken your bones, causing an increased risk of fractures and broken bones. High levels of uric acid and gout are more common in people with alcohol use disorder.

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Alcohol and Traumatic Injuries

Alcohol’s effect on cognitive and psychomotor functioning can have dangerous and potentially deadly physical consequences. Alcohol also can lower a person’s inhibitions, so you may be more likely to make hasty, irrational, or irresponsible actions that may contribute to a loss of control, which can lead to many consequences, including violence or accidents.20,21

  • Increased violent behavior, including homicide and intimate partner violence.
  • Increased risk of injury, including car accidents or accidental drowning.
  • Risk of suicide.
  • Risky sexual behaviors, which can increase the risk of unwanted pregnancy or contracting sexually transmitted diseases.

In addition to risking serious injury, the above consequences may also be deadly. Alcohol is a factor in about 60% of fatal burn injuries, drownings, and homicides; 50% of severe trauma injuries and sexual assaults; and 40% of fatal motor vehicle crashes, suicides, and fatal falls.22 Additionally, the effects of alcohol during pregnancy can be particularly extensive and devastating for both a mother and her child.

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Frequently Asked Questions Regarding Alcohol Health Risks


  1. Substance Abuse and Mental Health Services Administration (SAMHSA). (2019). Alcohol Use in Lifetime among Persons Aged 12 or Older, by Age Group and Demographic Characteristics: Percentages, 2018 and 2019.
  2. Centers for Disease Control and Prevention. (2021). Alcohol Use and Your Health.
  3. NHS. (2018). Risks: Alcohol misuse.
  4. Centers for Disease Control and Prevention. (2020). Dietary Guidelines for Americans.
  5. National Institute on Alcohol Abuse and Alcoholism. (2021). Alcohol Facts and Statistics.
  6. Centers for Disease Control and Prevention. (2021). Excessive Alcohol Deaths.
  7. Piano M. R. (2017). Alcohol’s Effects on the Cardiovascular System.
  8. National Institute on Alcohol Abuse and Alcoholism. (1999). Are Women More Vulnerable to Alcohol’s Effects?
  9. National Institute on Alcohol Abuse and Alcoholism. (2021). Alcohol and the Brain.
  10. Bode, C., & Bode, J. C. (1997). Alcohol’s role in gastrointestinal tract disorders. Alcohol health and research world, 21(1), 76–83.
  11. National Kidney Foundation. (2017). Drinking Alcohol Affects Your Kidneys.
  12. Maher J. J. (1997). Exploring alcohol’s effects on liver function. Alcohol health and research world, 21(1), 5–12.
  13. National Institute on Alcohol Abuse and Alcoholism. Alcohol’s Effects on the Body.
  14. Duke University Alcohol Pharmacology Education Partnership. Content: Repeated Use of Alcohol Can Cause Long-term Changes in the Brain.
  15. National Cancer Institute. (2018). Alcohol and Cancer Risk.
  16. Miller, S. C., Fiellin, D. A., Rosenthal, R. N., & Saitz, R. (2019). The ASAM Principles of Addiction Medicine, Sixth Edition. Philadelphia: Wolters Kluwer.
  17. Field, M., Wiers, R. W., Christiansen, P., Fillmore, M. T., & Verster, J. C. (2010). Acute alcohol effects on inhibitory control and implicit cognition: implications for loss of control over drinking. Alcoholism, Clinical and Experimental Research, 34(8), 1346–1352.
  18. Steele, C. M., & Southwick, L. (1985). Alcohol and social behavior I: The psychology of drunken excess. Journal of Personality and Social Psychology, 48(1), 18–34.
  19. Rethinking Drinking. (2021). Alcohol and Your Health.
  20. Centers for Disease Control and Prevention. (2021). Basics about FASDs.
  21. Centers for Disease Control and Prevention. (2020). Underage drinking
  22. Sarkola, T., & Eriksson, C. J. (2003). Testosterone increases in men after a low dose of alcohol. Alcoholism: Clinical and Experimental Research, 27(4), 682–685.
  23. Pahwa, R., Goyal, A., Bansal, P. & Jialal, I. (2020). Chronic Inflammation. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing.
  24. Wang, H. J., Zakhari, S., & Jung, M. K. (2010). Alcohol, inflammation, and gut-liver-brain interactions in tissue damage and disease development. World Journal of Gastroenterology, 16(11), 1304-1313.
  25. Bektas, A., Sen, R., & Ferrucci, L. (2016). Does a bit of alcohol turn off inflammation and improve health? Age and Ageing, 45(6), 747–748.
  26. Sarkar, D., Jung, M. K., & Wang, H. J. (2015). Alcohol and the Immune System. Alcohol Research: Current Reviews, 37(2), 153–155.
  27. National Institute on Alcohol Abuse and Alcoholism. (2000). Health risks and benefits of alcohol consumption. Alcohol Research & Health, 24(1), 5–11.
  28. BGSU Department of Recreation and Wellness. Alcohol Metabolism.
  29. Paton, A. (2005). Alcohol in the body. BMJ, 330(7482), 85–87.
  30. Peragallo, J., Biousse, V., & Newman, N. J. (2013). Ocular manifestations of drug and alcohol abuse. Current Opinion in Ophthalmology, 24(6), 566–573.
  31. Emanuele, M. A., Wezeman, F., & Emanuele, N. V. (2002). Alcohol’s effects on female reproductive function. Alcohol Research & Health, 26(4), 274–281.
Last Updated on Sep 15, 2022
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