According to a 2011 study, about 9 percent of the US population has used, abused, or become addicted to inhalants at some point in their lives – that is about 22.5 million people in the United States. Because many of these substances are legal household items, the most at-risk group for inhalant abuse and addiction is adolescents, under the age of 18. In one survey of people who had used inhalants for the first time in the prior 12 months, around 68 percent of these new users were under the age of 18. In another survey, 58 percent of people who abused inhalants started doing so by the end of 9 th grade. A third study found that around 20 percent of middle and high school students had abused inhalants at some point.
The mean age of first inhalant use or abuse is 13 years old in the US, with white and Hispanic children more likely to struggle with abuse and addiction problems involving inhalants than other socioeconomic groups. Inhalant abuse most often begins before tobacco, alcohol, marijuana, or other substance abuse.
Another group at risk for becoming addicted to inhalants – especially nitrous oxide – are dentists and dental hygienists. Although substance abuse and addiction risks are based on a variety of genetic, environmental, and psychological factors that are still being studied, those who work in the dental field and have this combination of substance abuse risk factors are more likely to struggle with addiction to nitrous oxide, because of access to this drug. Nitrous oxide is used in dental applications as a sedative for oral surgery, such as during wisdom teeth removal surgery. According to a study from the ADA Dentist Health and Awareness Committee, around 5 percent of dentists with substance abuse issues abuse nitrous oxide.